| Do 15 juli 2021 (O) | 20:00 | ROHDA Raalte | 2 – 4 | SVZW |
| Di 10 aug 2021 (O) | 20:00 | ROHDA Raalte | 2 – 0 | VVG’25 |
| Za 14 aug 2021 (O) | 17:00 | ROHDA Raalte | 2 – 1 | vv Berkum |
| Di 17 aug 2021(O) | 20:00 | vv Staphorst | 5 – 1 | ROHDA Raalte |
| Di 24 aug 2021 (O) | 20:15 | ROHDA Raalte | 2 – 0 | Alcides |
| Za 28 aug 2021 (O) | 13:00 | WVF | 1 – 5 | ROHDA Raalte |
| Di 31 aug 2021(O) | 20:00 | SVI | 2 – 2 | ROHDA Raalte |
| Za 4 sep 2021 (B) | 17:00 | ROHDA Raalte | 1 – 2 | Vroomshoopse Boys |
| Di 7 sep 2021 (O) | 20:15 | ROHDA Raalte | 1 – 1 | ZAC |
| Zo 12 sep (B) | 14:00 | FC Suryoye-Mediterraneo | 0 – 1 | ROHDA Raalte |
| Zo 19 sep 2021 (B) | 14:00 | ROHDA Raalte | – | Sv Grol |
| Di 21 sep 2021 | 20:00 | Training | ||
| Di 23 sep 2021 | 20:00 | Training | ||
| Zo 26 sep 2021 (C) | 14:00 | ROHDA Raalte | – | MASV |
| Zo 3 okt 2021 (C) | 14:00 | RKHVV | – | ROHDA Raalte |
| Zo 10 okt 2021 (C) | 14:00 | TVC’28 | – | ROHDA Raalte |
| Zo 17 okt 2021 (C) | 14:00 | ROHDA Raalte | – | Dalfsen |
| Zo 24 okt 2021 (C) | 14:00 | Heino | – | ROHDA Raalte |
| Zo 31 okt 2021 (C) | 14:00 | ROHDA Raalte | – | Columbia |
| Zo 7 nov 2021 (C) | 14:00 | BVC’12 | – | ROHDA Raalte |
| Zo 21 nov 2021 (C) | 14:00 | ROHDA Raalte | – | De Bataven |
| Zo 28 nov 2021 (C) | 14:00 | Stevo | – | ROHDA Raalte |
| Zo 5 dec 2021 (C) | 14:00 | ROHDA Raalte | – | SC Bemmel |
| Zo 12 dec 2021 (C) | 14:00 | Tubantia | – | ROHDA Raalte |
| Zo 23 jan 2022 (C) | 14:00 | Voorwaarts Twello | – | ROHDA Raalte |
| Zo 30 jan 2022 (C) | 14:00 | ROHDA Raalte | – | FC Winterswijk |
| Zo 6 feb 2022 (C) | 14:00 | Dalfsen | – | ROHDA Raalte |
| Zo 13 feb 2022 (C) | 14:00 | ROHDA Raalte | – | TVC’28 |
| Zo 6 mrt 2022 (C) | 14:00 | De Bataven | – | ROHDA Raalte |
| Zo 13 mrt 2022 (C) | 14:00 | ROHDA Raalte | – | BVC’12 |
| Zo 20 mrt 2022 (C) | 14:00 | Columbia | – | ROHDA Raalte |
| Zo 27 mrt 2022 (C) | 14:00 | ROHDA Raalte | – | Tubantia |
| Zo 3 apr 2022 (C) | 14:00 | FC Winterswijk | – | ROHDA Raalte |
| Zo 10 apr 2022 (C) | 14:00 | ROHDA Raalte | – | Heino |
| Zo 24 apr 2022 (C) | 14:00 | ROHDA Raalte | – | Voorwaarts Twello |
| Zo 1 mei 2022 (C) | 14:30 | MASV | – | ROHDA Raalte |
| Zo 15 mei 2022 (C) | 14:00 | ROHDA Raalte | – | Stevo |
| Zo 22 mei 2022 (C) | 14:00 | Sc Bemmel | – | ROHDA Raalte |
| Zo 29 mei 2022 (C) | 14:00 | ROHDA Raalte | – | RKHVV |
(B) = Beker
(C) = Competitie
(O) = Oefenwedstrijd
(T) = Toernooi
(S) = Schaduwwedstrijd
(N) = Nacompetitie
